JB,
I feel history about to repeat itself. I'm remembering when I 
received a query years back from an unknown writer whose manuscript 
caught my attention. I knew he had something exciting going on but I 
didn't make an essential connection with the work-- didn't
 quite 'get' it. I told him the truth, he found an agent elsewhere, and 
has since had more than a few bestsellers. That unknown writer is 
Christopher Moore. 
With your book, I have that same certainty about its potential but 
also that same underlying disconnect. But I want to recommend a 
colleague who might be a good fit. His name is __________ and you can 
reach him at wouldntyouliketoknow@literaryagents.com. Tell him I sent you.
Good luck and all the best,
Lisa